Enabling MRI guided vascular interventions
EmeryGlide
We enable interventions at optimal visibility and gold standard flow without radiation risk.
Nano4Imaging is developing a suite of MRI compatible devices and markers that support common and complicated interventional vascular procedures. Cardiac MRI, Interventional Radiology and Radiotherapy are clinical area´s to benefit from this unique technology that can be employed in any conventional MRI suite*
*Technology has been tested safe up to 3Tesla according to applicable ASTM and ISO standards for heating, torque, and visibility (artefacts)
Clinical perspective
The societal burden of CVD remains high and despite state of the art cathab procedures, MRI based interventional cardiology is expected to bring strong patient and staff benefits. Our vision is to overcome current challenges by our medical devices, marking technology and software solutions to assist guidance.
MR based interventional cardiology
Challenges
Opportunities
Guide wires dedicated for MRI
The EmeryGlide (TM) guidewire is an MRI conditional guide wire which is safe to use in 1.5 and 3.0 Tesla for real-time interventions according to ASTM F2182, F2052, F2053 and F2213 standards. The wire has discrete MRI markers and the entire wire is radiopaque (ASTM F640-79). In addition its construction with a double internal winding and the entire body and tip are packed into one sleeve to prevent detachment of tip and breaking of the internal core. The MRWire has CE 0344, FDA 510 K approval and is registered by Health Canada.
Applicable product standard:
sterile, single-use intravascular introducers, dilators and guidewires (ISO/DIS 11070:2013).
Video below:
MR image (1.5 tesla, GRE) showing discrete markers in the tip and distal from the tip create MRI image artefacts tested by ASTM F2119. The image above shows the artifacts evenly distributed over a guide wire inserted in the right renal artery, followed by balloon dilatation, pull-back of catheter and stenting (large artefact). For more details see Kos et al (2009)
Tip shape | Straight or angled |
Tip properties | Soft tip |
Tip length | 40 mm |
Core-shaft-tip | One body |
Material | Fibre-reinforced composite |
Outer Sleeve | PTFE |
MRI visibility | Straight tip– passive markers at discrete positions 0,2,4 cm from tip |
Angled tip – passive markers at discrete positions 0,2,4 cm from tip | |
Marker technology | MR conditional |
Technical properties | One body |
Diameter | 0.89 mm (0.035 inch) |
Length | 180 cm (other lenghts on demand) |
Manufacturer | CMI Contract Medical International GmbH, Dresden (Germany) |
Testing
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