Enabling MRI guided vascular interventions


We enable interventions at optimal visibility and gold standard flow without radiation risk.

Nano4Imaging is developing a suite of MRI compatible devices and markers that support common and complicated interventional vascular procedures. Cardiac MRI, Interventional Radiology and Radiotherapy are clinical area´s to benefit from this unique technology that can be employed in any conventional MRI suite*

*Technology has been tested safe up to 3Tesla according to applicable ASTM and ISO standards for heating, torque, and visibility (artefacts)

Technology and Vision

Societal burden of CVD

  • Number one cause of death

  • €210B cost to society in EU

  • Largest contributer of DALY

  • Growing number of chronic CVD patients

CT guided interventional cardiology

  • Easy to use centralized cath-labs

  • Sub-optimal clinical outcomes

  • Radiation exposure for patients/staff

  • Potential for organ toxicity in some patients

The societal burden of CVD remains high and despite state of the art cathab procedures, MRI based interventional cardiology is expected to bring strong patient and staff benefits. Our vision is to overcome current challenges by our medical devices, marking technology and software solutions to assist guidance.

MR based interventional cardiology

  • Radiation free alternative to CT

  • Higher image resolution

  • Improved clinical outcome


  • Sub-optimal MR compatible quidewires

  • Inaccurate tracking softwares

  • Lack of enough clinical evidence and high costs


  • Strong clinical push

  • Innovative catheter and guidewire designs

  • Al powered tracking softwares

Guide wires dedicated for MRI

The  EmeryGlide (TM) guidewire is an MRI conditional guide wire which is safe to use in 1.5 and 3.0 Tesla for real-time interventions according to ASTM F2182, F2052, F2053 and F2213 standards. The wire has discrete MRI markers and the entire  wire is radiopaque (ASTM F640-79). In addition its construction with a double internal winding and the entire body and tip are packed into one sleeve to prevent detachment of tip and breaking of the internal  core. The MRWire has CE 0344, FDA 510 K approval and is registered by Health Canada.

Applicable product standard:
sterile, single-use intravascular introducers, dilators and guidewires (ISO/DIS 11070:2013). The product is not certified or availble in the USA.

Video below:
MR image (1.5 tesla, GRE) showing discrete markers in the tip and distal from the tip create MRI image artefacts tested by ASTM F2119. The image above shows the artifacts evenly distributed over a guide wire inserted in the right renal artery, followed by ballon dilatation, pull-back of catheter and stenting (large artifact). For more details see Kos et al (2009)

Tip shape Straight or angled
Tip properties Soft tip
Tip length 40 mm
Core-shaft-tip One body
Material Fibre-reinforced composite
Outer Sleeve PTFE
MRI visibility Straight tip– passive markers at discrete positions 0,2,4 cm from tip
Angled tip – passive markers at discrete positions 0,2,4 cm from tip
Marker technology MR conditional
Technical properties One body
Diameter 0.89 mm (0.035 inch)
Length 180 cm (other lenghts on demand)
Manufacturer CMI Contract Medical International GmbH, Dresden (Germany)


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Discover the Possibilities

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